Mouse Model for Tubular Injury (TI)

KTD; Kidney Tubular Damage

• Urinary system

• Product No.DSI630Mu02
• Organism SpeciesMus musculus (Mouse) Same name, Different species.
• • All
  • Human
  • Mouse
  • Rat
  • Cavia
  • Rabbit
  • Simian
  • Caprine
  • Ovine
  • Equine
  • Bovine
  • Porcine
  • Gallus
  • Canine
  • Others
  • Multi-species
  • Pan-species
• Prototype SpeciesHuman
• Sourceinduced by Intravenous injection of mercury chloride
• Model Animal StrainsBalb/c Mice(SPF), healthy, male, age: 8~10weeks, body weight:30g~35g.
• Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
• Modeling Period4-6 weeks
• Modeling MethodAdult male mice weight 25 ~ 30 g, HgCl2 prepared with physiological saline as the solution of 0.125 g/L; The tail vein of mice by 10 ml/kg body weight dose injection HgCl2 solution. In the scheduled time of anesthesia posterior divisions arterial blood, serum creatinine and urea nitrogen determination; To be put to death animals quickly extract the kidney, saline wash, blot, part of the kidney tissues after processing measure renal lipid peroxide (LPO) and mercury, calcium, iron, zinc, copper and other trace elements; Take part after kidney purple fabric specimen fixed fluid, paraffin embedding, normal tissue section, HE stain, light microscopy observation.
• Applicationsn/a
• Download n/a
• UOM Each case
• FOB US$
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