Mouse Model for Hemopoietic Microenvironment Injury (HMI)
- Product No.UDSI746Mu01
 - Organism SpeciesMus musculus (Mouse) Same name, Different species.
 - Prototype SpeciesHuman
 - SourceInduced by Co60γ Irradiate to nude mice
 - Model Animal StrainsBALB/c -nu/nu nude mice (SPF), 6 week, body weight: 18~22g
 - Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
 - Modeling Period3 weeks
 - Modeling Method1. The gamma ray irradiation (Co60γ) with single dose of 3, 4, 5, 6, and 7 Gy was used to simulate the functional damage of the mild, moderate and severe hematopoietic microenvironment.
2. After irradiation, the general situation of the nude mice, the changes of hemogram, megakaryocyte count and the formation of the colony forming unit (colony forming unit-fibroblast, CFU-F) of bone marrow stromal cells were observed. The mortality of nude mice after irradiation in 21d was recorded and the survival rate was calculated. - ApplicationsDisease Model
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 - UOM Each case
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Model Evaluation of the Mouse Model for Hemopoietic Microenvironment Injury (HMI)
Pathological Results of the Mouse Model for Hemopoietic Microenvironment Injury (HMI)
Cytokines Level of the Mouse Model for Hemopoietic Microenvironment Injury (HMI)
Statistical Analysis of the Mouse Model for Hemopoietic Microenvironment Injury (HMI)
SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.
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                    Tissue/Sections Customized Service
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                            Immunohistochemistry (IHC) Experiment Service
                            Small Animal In Vivo Imaging Experiment Service
                            Small Animal Micro CT Imaging Experiment Service
                            Small Animal MRI Imaging Experiment Service
                            Small Animal Ultrasound Imaging Experiment Service
                            Transmission Electron Microscopy (TEM) Experiment Service
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                            Learning and Memory Behavioral Experiment Service
                            Anxiety and Depression Behavioral Experiment Service
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                            Nitric Oxide Assay Kit (A012)
                            Nitric Oxide Assay Kit (A013-2)
                            Total Anti-Oxidative Capability Assay Kit(A015-2)
                            Total Anti-Oxidative Capability Assay Kit (A015-1)
                            Superoxide Dismutase Assay Kit
                            Fructose Assay Kit (A085)
                            Citric Acid Assay Kit (A128 )
                            Catalase Assay Kit
                            Malondialdehyde Assay Kit
                            Glutathione S-Transferase Assay Kit
                            Microscale Reduced Glutathione assay kit
                            Glutathione Reductase Activity Coefficient Assay Kit
                            Angiotensin Converting Enzyme Kit
                            Glutathione Peroxidase (GSH-PX) Assay Kit
                            Cloud-Clone Multiplex assay kits
                                            
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| Catalog No. | Organism species: Mus musculus (Mouse) | Applications (RESEARCH USE ONLY!) | 
| UDSI746Mu01 | Mouse Model for Hemopoietic Microenvironment Injury (HMI) | Disease Model | 
