Rat Model for Calvarial Defects (CD)

Calvarial Bone Defects,Skull Defects,Cranial defects

• Product No.DSI844Ra01
• Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
• • All
  • Human
  • Mouse
  • Rat
  • Cavia
  • Rabbit
  • Simian
  • Caprine
  • Ovine
  • Equine
  • Bovine
  • Porcine
  • Gallus
  • Canine
  • Others
  • Multi-species
  • Pan-species
• Prototype SpeciesHuman
• SourceSkull drilling
• Model Animal StrainsSD Rats(SPF), healthy, male, body weight 180g~200g
• Modeling Grouping1.Randomly divided into six group: Control group, Model group, Positive drug group and Tested drug group.
• Modeling Period6w
• Modeling MethodThe rats were subjected to abdominal anesthesia. After the effect of anesthesia, the skull area was covered with skin, disinfected and towel, and the rats were placed in a prone position. A 3cm longitudinal incision was made in the skull of the rats, the skin, subcutaneous tissue and muscle-periosteum layer were cut and flaps were performed, and the skull bone plate was exposed by blunt separation.Two round full-thickness periosteum bone defects with diameters of 5mm were made on both sides of the cranial suture with a high speed drill with a 5mm outer diameter.
  The animals were sacrificed 8 weeks after operation, and the skull and periosteum of the defect site were taken and preserved in 10% neutral formalin solution.
• ApplicationsBone graft materials are commonly used to regenerate bone defects
• Download n/a
• UOM Each case
• FOB US$ 240
  For more details, please contact local distributors!