Wilms Tumor Protein (WT1)
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WAGR; GUD; WIT-2; WT33
 HGNC 12796
 MGI 98968
 PubMed 22215675
 RGD 3974
 UniProt P19544
 USCN F116
 Wiki WT1
Wilms Tumor Protein (WT1)
Wilms tumor protein is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a subset of patients with Wilms' tumor, the gene's namesake. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.The WT1 protein has been found to bind a host of cellular factors, e.g. p53, a known tumor suppressor.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF116Hu01 Recombinant Wilms Tumor Protein (WT1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAF116Hu21 Monoclonal Antibody to Wilms Tumor Protein (WT1) WB, ICC, IHC-P, IHC-F, ELISA
PAF116Hu01 Polyclonal Antibody to Wilms Tumor Protein (WT1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEF116Hu ELISA Kit for Wilms Tumor Protein (WT1) Enzyme-linked immunosorbent assay
SCF116Hu CLIA Kit for Wilms Tumor Protein (WT1) Chemiluminescent immunoassay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a