Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B)
CD120B; P75; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR2; TNFR80; P75tnfr; Tumor necrosis factor receptor 2; p80 TNF-alpha receptor; Etanercept
TNFRSF1B is a human gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1A. The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB504Hu01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Positive Control; Immunogen; SDS-PAGE; WB. |
APB504Hu01 | Active Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Cell culture; Activity Assays. | |
EPB504Hu61 | Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB504Hu01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | WB; IHC; ICC; IP. |
MAB504Hu21 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | WB; IHC; ICC; IP. | |
Assay Kits | SEB504Hu | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB504Mu01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Positive Control; Immunogen; SDS-PAGE; WB. |
EPB504Mu61 | Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APB504Mu61 | Active Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Cell culture; Activity Assays. | |
Antibodies | PAB504Mu01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | WB; IHC; ICC; IP. |
LAB504Mu71 | Biotin-Linked Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | WB; IHC; ICC. | |
Assay Kits | n/a | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB504Ra01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Positive Control; Immunogen; SDS-PAGE; WB. |
EPB504Ra61 | Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APB504Ra61 | Active Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Cell culture; Activity Assays. | |
Antibodies | PAB504Ra01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | WB; IHC; ICC; IP. |
MAB504Ra21 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | WB; IHC; ICC; IP. | |
Assay Kits | SEB504Ra | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) | Enzyme-linked immunosorbent assay for Antigen Detection. |