Carboxypeptidase B2 (CPB2)
TAFI; CPU; PCPB; Thrombin Activatable Fibrinolysis Inhibitor; Plasma Carboxypeptidase B; Carboxypeptidase U
TAFI, Thrombin Activatable Fibrinolytic Inhibitor, (also known as carboxypeptidase U and plasma carboxypeptidase B) is a 60,000 D molecular ratio glycoprotein (proenzyme form) present in rabbit plasma1 that modulates fibrinolysis in vivo. This proenzyme is converted to a 35,000 D molecular ratio active form, TAFIa, following proteolytic cleavage by the thrombin/ thrombomodulin complex. TAFIa possesses carboxypeptidase activity with a preference for cleaving lysine and arginine residues from the c-terminus of proteins. Modulation of fibrinolysis occurs when TAFIa cleaves C-terminal arginine and lysine residues of partially degraded fibrin.2,4,5 The removal of the c-terminus arginine and lysine residues from fibrin inhibits the continued degradation of fibrin by tPA activated plasmin.3
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA615Hu01 | Recombinant Carboxypeptidase B2 (CPB2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA615Hu01 | Polyclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC; IP. |
MAA615Hu22 | Monoclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC; IP. | |
Assay Kits | SEA615Hu | ELISA Kit for Carboxypeptidase B2 (CPB2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA615Mu01 | Recombinant Carboxypeptidase B2 (CPB2) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA615Mu02 | Recombinant Carboxypeptidase B2 (CPB2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA615Mu03 | Recombinant Carboxypeptidase B2 (CPB2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA615Mu01 | Polyclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC; IP. |
PAA615Mu03 | Polyclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC; IP. | |
PAA615Mu02 | Polyclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC; IP. | |
LAA615Mu71 | Biotin-Linked Polyclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC. | |
LAA615Mu81 | FITC-Linked Polyclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC; IF. | |
Assay Kits | SEA615Mu | ELISA Kit for Carboxypeptidase B2 (CPB2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA615Ra01 | Recombinant Carboxypeptidase B2 (CPB2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA615Ra01 | Polyclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC; IP. |
MAA615Ra21 | Monoclonal Antibody to Carboxypeptidase B2 (CPB2) | WB; IHC; ICC; IP. | |
Assay Kits | SEA615Ra | ELISA Kit for Carboxypeptidase B2 (CPB2) | Enzyme-linked immunosorbent assay for Antigen Detection. |