Ryanodine Receptor 1, Skeletal (RYR1)
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CCO; MHS; MHS1; RYDR; RYR; SKRR; Central Core Disease Of Muscle; Skeletal muscle calcium release channel
 HGNC 10483
 MGI 99659
 PubMed 19191333
 RGD 1586637
 UniProt P21817
 USCN C773
 Wiki RYR1
Ryanodine Receptor 1, Skeletal (RYR1)
Ryanodine receptor 1 is a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.
Communication between transverse-tubules and sarcoplasmic reticulum. Contraction of skeletal muscle is triggered by release of calcium ions from SR following depolarization of T-tubules.Skeletal muscle and brain (cerebellum and hippocampus).
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC773Hu01 Recombinant Ryanodine Receptor 1, Skeletal (RYR1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC773Hu21 Monoclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1) WB, ICC, IHC-P, IHC-F, ELISA
PAC773Hu01 Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC773Hu ELISA Kit for Ryanodine Receptor 1, Skeletal (RYR1) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC773Mu01 Recombinant Ryanodine Receptor 1, Skeletal (RYR1) SDS-PAGE; WB; ELISA; IP.
RPC773Mu02 Recombinant Ryanodine Receptor 1, Skeletal (RYR1) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC773Mu01 Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1) WB, ICC, IHC-P, IHC-F, ELISA
PAC773Mu02 Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC773Mu ELISA Kit for Ryanodine Receptor 1, Skeletal (RYR1) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC773Ra01 Recombinant Ryanodine Receptor 1, Skeletal (RYR1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC773Ra21 Monoclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1) WB, ICC, IHC-P, IHC-F, ELISA
PAC773Ra01 Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC773Ra ELISA Kit for Ryanodine Receptor 1, Skeletal (RYR1) Enzyme-linked immunosorbent assay