Amyloid Precursor Protein (APP)
AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein
Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation and neural plasticity. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates amyloid beta (Aβ), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.Several alternative splicing isoforms of APP have been observed in humans, ranging in length from 365 to 770 amino acids, with certain isoforms preferentially expressed in neurons; changes in the neuronal ratio of these isoforms have been associated with Alzheimer's disease.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB020Hu01 | Recombinant Amyloid Precursor Protein (APP) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB020Hu02 | Recombinant Amyloid Precursor Protein (APP) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPB020Hu03 | Recombinant Amyloid Precursor Protein (APP) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB020Hu01 | Polyclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. |
MAB020Hu22 | Monoclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. | |
MAB020Hu23 | Monoclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. | |
PAB020Hu02 | Polyclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. | |
PAB020Hu03 | Polyclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. | |
Assay Kits | SEB020Hu | ELISA Kit for Amyloid Precursor Protein (APP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCB020Hu | CLIA Kit for Amyloid Precursor Protein (APP) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB020Mu01 | Recombinant Amyloid Precursor Protein (APP) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB020Mu02 | Recombinant Amyloid Precursor Protein (APP) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB020Mu01 | Polyclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. |
PAB020Mu02 | Polyclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. | |
LAB020Mu71 | Biotin-Linked Polyclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC. | |
LAB020Mu81 | FITC-Linked Polyclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IF. | |
Assay Kits | SEB020Mu | ELISA Kit for Amyloid Precursor Protein (APP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB020Ra01 | Recombinant Amyloid Precursor Protein (APP) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB020Ra01 | Polyclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. |
MAB020Ra21 | Monoclonal Antibody to Amyloid Precursor Protein (APP) | WB; IHC; ICC; IP. | |
Assay Kits | SEB020Ra | ELISA Kit for Amyloid Precursor Protein (APP) | Enzyme-linked immunosorbent assay for Antigen Detection. |