Amyloid Precursor Protein (APP)
AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein
 HGNC 620
 MGI 88059
 RGD 2139
 UniProt P05067
 USCN B020
Amyloid Precursor Protein (APP)
Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation and neural plasticity. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates amyloid beta (Aβ), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.Several alternative splicing isoforms of APP have been observed in humans, ranging in length from 365 to 770 amino acids, with certain isoforms preferentially expressed in neurons; changes in the neuronal ratio of these isoforms have been associated with Alzheimer's disease.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB020Hu01 Recombinant Amyloid Precursor Protein (APP) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB020Hu22 Monoclonal Antibody to Amyloid Precursor Protein (APP) WB, ICC, IHC-P, IHC-F, ELISA
PAB020Hu01 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB020Hu ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay
SCB020Hu CLIA Kit for Amyloid Precursor Protein (APP) Chemiluminescent immunoassay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB020Mu01 Recombinant Amyloid Precursor Protein (APP) SDS-PAGE; WB; ELISA; IP.
RPB020Mu02 Recombinant Amyloid Precursor Protein (APP) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB020Mu01 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB, ICC, IHC-P, IHC-F, ELISA
PAB020Mu02 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB, ICC, IHC-P, IHC-F, ELISA
PAB020Mu71 Biotin-Linked Antibody to Amyloid Precursor Protein (APP) IHC;WB;ELISA
PAB020Mu81 FITC-Linked Antibody to Amyloid Precursor Protein (APP) IHC;ICC;IF;WB
Assay Kits SEB020Mu ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB020Ra01 Recombinant Amyloid Precursor Protein (APP) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB020Ra21 Monoclonal Antibody to Amyloid Precursor Protein (APP) WB, ICC, IHC-P, IHC-F, ELISA
PAB020Ra01 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB020Ra ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay