Cavia Model for Motor Neuron Disease (MND)
- Product No.DSI824Gu01
- Organism SpeciesCavia (Guinea pig ) Same name, Different species.
- Prototype SpeciesHuman
- SourceInduced by immunized with purified bovine spinal cord anterior horn motor neurons
- Model Animal StrainsGuinea pig, male, healthy, body weight: 480~500g
- Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
- Modeling Period16w~18w
- Modeling Method1. Guinea pigs were immunized with fresh bovine spinal cord anterior horn homogenate, and 10 parts were injected subcutaneously at the back of the guinea pigs, each time for 4 weeks, for a total of 5 times.
2. The changes of light microscope and ultrastructure of spinal cord: anterior root and sciatic nerve were observed. Results the weight of guinea pigs decreased significantly after fourth immunization. Degeneration and loss of motor neurons in the anterior horn of the spinal cord. - ApplicationsDisease Model
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- UOM Each case
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FOB
US$ 300
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Model Evaluation of the Cavia Model for Motor Neuron Disease (MND)
Pathological Results of the Cavia Model for Motor Neuron Disease (MND)
Cytokines Level of the Cavia Model for Motor Neuron Disease (MND)
Statistical Analysis of the Cavia Model for Motor Neuron Disease (MND)
SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.
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Immunohistochemistry (IHC) Experiment Service
Small Animal In Vivo Imaging Experiment Service
Small Animal Micro CT Imaging Experiment Service
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Nitric Oxide Assay Kit (A013-2)
Total Anti-Oxidative Capability Assay Kit(A015-2)
Total Anti-Oxidative Capability Assay Kit (A015-1)
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Catalase Assay Kit
Malondialdehyde Assay Kit
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Microscale Reduced Glutathione assay kit
Glutathione Reductase Activity Coefficient Assay Kit
Angiotensin Converting Enzyme Kit
Glutathione Peroxidase (GSH-PX) Assay Kit
Cloud-Clone Multiplex assay kits
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Catalog No. | Organism species: Cavia (Guinea pig ) | Applications (RESEARCH USE ONLY!) |
DSI824Gu01 | Cavia Model for Motor Neuron Disease (MND) | Disease Model |