Zona Pellucida Glycoprotein 3, Sperm Receptor (ZP3)
ZP3A; ZP3B
 HGNC 13189
 MGI 99215
 RGD 620606
 UniProt P21754
 USCN F585
Zona Pellucida Glycoprotein 3, Sperm Receptor (ZP3)
During the process of fertilization, the initial interaction between male and female gametes is mediated by a sperm receptor, designated ZP3, which resides in the extracellular glycoprotein matrix (zona pellucida) surrounding the oocyte. The sperm receptor function of the ZP3 molecule plays a key role in the first step of the fertilization process. Following sperm-oocyte binding, ZP3 triggers the sperm acrosome reaction that releases the protein machinery enabling a spermatozoon to penetrate the zona pellucida. The distribution of these 3 patterns was significantly different between the Caucasian and Japanese populations, as indicated by ZP3-372 allele frequencies of 69 and 21%, respectively. Provided that ZP3-372 mRNA is translated in vivo, differences in the protein gene product might have an impact on human zona pellucida composition.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a