Zinc Finger, MYM-Type Protein 2 (ZMYM2)
FIM; MYM; RAMP; SCLL; ZNF198; Rearranged In An Atypical Myeloproliferative Disorder
 HGNC 12989
 MGI 1923257
 PubMed 23594707
 RGD 1593255
 UniProt Q9UBW7
 USCN J766
 Wiki ZMYM2
Zinc Finger, MYM-Type Protein 2 (ZMYM2)
These translocations were associated with aberrant transcripts in which 4 predicted zinc finger domains, contributed by the widely expressed chromosome 13 gene ZNF198, were fused to the FGFR1 tyrosine-kinase domain. Transient expression studies showed that the ZNF198-FGFR1 fusion transcript directed the synthesis of an approximately 87-kD polypeptide, localizing predominantly to the cytoplasm.
The novel sequence that was fused to FGFR1, comprising the 5-prime end of the fusion transcript, was mapped to chromosome 13 with the CEPH mega-YAC library and the Genebridge 4 radiation hybrid panel. The findings were consistent with the pericentromeric 13q11-q12 assignments for the t(8;13) cytogenetic breakpoints.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a