X-Ray Repair Cross Complementing 5 (XRCC5)
XRCC-5; KARP-1; KARP1; KU80; KUB2; Ku86; NFIV; Lupus Ku Autoantigen Protein P80; X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5
 HGNC 12833
 MGI 104517
 RGD 3976
 UniProt P13010
 USCN D013
X-Ray Repair Cross Complementing 5 (XRCC5)
Ku80 is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD013Hu01 Recombinant X-Ray Repair Cross Complementing 5 (XRCC5) SDS-PAGE; WB; ELISA; IP.
Antibodies MAD013Hu21 Monoclonal Antibody to X-Ray Repair Cross Complementing 5 (XRCC5) WB, ICC, IHC-P, IHC-F, ELISA
PAD013Hu01 Polyclonal Antibody to X-Ray Repair Cross Complementing 5 (XRCC5) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SED013Hu ELISA Kit for X-Ray Repair Cross Complementing 5 (XRCC5) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD013Mu01 Recombinant X-Ray Repair Cross Complementing 5 (XRCC5) SDS-PAGE; WB; ELISA; IP.
RPD013Mu02 Recombinant X-Ray Repair Cross Complementing 5 (XRCC5) SDS-PAGE; WB; ELISA; IP.
Antibodies PAD013Mu01 Polyclonal Antibody to X-Ray Repair Cross Complementing 5 (XRCC5) IWB, ICC, IHC-P, IHC-F, ELISA
PAD013Mu02 Polyclonal Antibody to X-Ray Repair Cross Complementing 5 (XRCC5) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SED013Mu ELISA Kit for X-Ray Repair Cross Complementing 5 (XRCC5) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a