Wolfram Syndrome Protein 1 (WFS1)
DFNA14; DFNA38; DFNA6; DIDMOAD; WFRS; WFS; Wolframin
Wolframin is a transmembrane protein.Wolframin appears to function as a cation-selective ion channel.Mutations in this gene are associated with an autosomal recessive syndrome characterized by insulin-dependent diabetes mellitus and bilateral progressive optic atrophy, usually presenting in childhood or early adult life. Diverse neurologic symptoms, including a predisposition to psychiatric illness, may also be associated with this disorder. A large number and variety of mutations in this gene, particularly in exon 8, can be associated with this syndrome. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6).Highly expressed in heart followed by brain, placenta, lung and pancreas. Weakly expressed in liver, kidney and skeletal muscle. Also expressed in islet and beta-cell insulinoma cell line.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPL118Hu01 | Recombinant Wolfram Syndrome Protein 1 (WFS1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAL118Hu01 | Polyclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. |
MAL118Hu21 | Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. | |
MAL118Hu22 | Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. | |
MAL118Hu23 | Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. | |
MAL118Hu24 | Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. | |
MAL118Hu25 | Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. | |
Assay Kits | SEL118Hu | ELISA Kit for Wolfram Syndrome Protein 1 (WFS1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCL118Hu | CLIA Kit for Wolfram Syndrome Protein 1 (WFS1) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPL118Mu01 | Recombinant Wolfram Syndrome Protein 1 (WFS1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPL118Mu02 | Recombinant Wolfram Syndrome Protein 1 (WFS1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAL118Mu01 | Polyclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. |
PAL118Mu02 | Polyclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. | |
Assay Kits | SEL118Mu | ELISA Kit for Wolfram Syndrome Protein 1 (WFS1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCL118Mu | CLIA Kit for Wolfram Syndrome Protein 1 (WFS1) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPL118Ra01 | Recombinant Wolfram Syndrome Protein 1 (WFS1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAL118Ra01 | Polyclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. |
MAL118Ra21 | Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) | WB; IHC; ICC; IP. | |
Assay Kits | SEL118Ra | ELISA Kit for Wolfram Syndrome Protein 1 (WFS1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCL118Ra | CLIA Kit for Wolfram Syndrome Protein 1 (WFS1) | Chemiluminescent immunoassay for Antigen Detection. |