Wolfram Syndrome Protein 1 (WFS1)
[ Edit ]
DFNA14; DFNA38; DFNA6; DIDMOAD; WFRS; WFS; Wolframin
 HGNC 12762
 MGI 1328355
 PubMed 16195229
 RGD 68954
 UniProt O76024
 USCN L118
 Wiki WFS1
Wolfram Syndrome Protein 1 (WFS1)
Wolframin is a transmembrane protein.Wolframin appears to function as a cation-selective ion channel.Mutations in this gene are associated with an autosomal recessive syndrome characterized by insulin-dependent diabetes mellitus and bilateral progressive optic atrophy, usually presenting in childhood or early adult life. Diverse neurologic symptoms, including a predisposition to psychiatric illness, may also be associated with this disorder. A large number and variety of mutations in this gene, particularly in exon 8, can be associated with this syndrome. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6).Highly expressed in heart followed by brain, placenta, lung and pancreas. Weakly expressed in liver, kidney and skeletal muscle. Also expressed in islet and beta-cell insulinoma cell line.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL118Hu01 Recombinant Wolfram Syndrome Protein 1 (WFS1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAL118Hu21 Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) WB, ICC, IHC-P, IHC-F, ELISA
PAL118Hu01 Polyclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEL118Hu ELISA Kit for Wolfram Syndrome Protein 1 (WFS1) Enzyme-linked immunosorbent assay
SCL118Hu CLIA Kit for Wolfram Syndrome Protein 1 (WFS1) Chemiluminescent immunoassay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL118Mu01 Recombinant Wolfram Syndrome Protein 1 (WFS1) SDS-PAGE; WB; ELISA; IP.
RPL118Mu02 Recombinant Wolfram Syndrome Protein 1 (WFS1) SDS-PAGE; WB; ELISA; IP.
Antibodies PAL118Mu01 Polyclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) WB, ICC, IHC-P, IHC-F, ELISA
PAL118Mu02 Polyclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEL118Mu ELISA Kit for Wolfram Syndrome Protein 1 (WFS1) Enzyme-linked immunosorbent assay
SCL118Mu CLIA Kit for Wolfram Syndrome Protein 1 (WFS1) Chemiluminescent immunoassay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL118Ra01 Recombinant Wolfram Syndrome Protein 1 (WFS1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAL118Ra21 Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) WB, ICC, IHC-P, IHC-F, ELISA
PAL118Ra01 Polyclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEL118Ra ELISA Kit for Wolfram Syndrome Protein 1 (WFS1) Enzyme-linked immunosorbent assay
SCL118Ra CLIA Kit for Wolfram Syndrome Protein 1 (WFS1) Chemiluminescent immunoassay