Vinculin (VCL)
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MVCL; Metavinculin
 HGNC 12665
 MGI 98927
 PubMed 14702644
 RGD 1311217
 UniProt P18206
 USCN B839
 Wiki Vinculin
Vinculin (VCL)
In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Its sequence is 20-30% homologous to α-catenin, which serves a similar function.
Vinculin is a 117 kDa cytoskeletal protein with 1066 amino acids. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. Vinculin consists of a globular head domain that contains binding sites for talin and α-actinin as well as a tyrosine phosphorylation site, while the tail region contains binding sites for F-actin, paxillin and lipids.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB839Hu01 Recombinant Vinculin (VCL) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB839Hu22 Monoclonal Antibody to Vinculin (VCL) WB, ICC, IHC-P, IHC-F, ELISA
PAB839Hu01 Polyclonal Antibody to Vinculin (VCL) WB, ICC, IHC-P, IHC-F, ELISA
PAB839Hu71 Biotin-Linked Antibody to Vinculin (VCL) IHC;WB;ELISA
Assay Kits SEB839Hu ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB839Mu01 Recombinant Vinculin (VCL) SDS-PAGE; WB; ELISA; IP.
RPB839Mu02 Recombinant Vinculin (VCL) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB839Mu01 Polyclonal Antibody to Vinculin (VCL) WB, ICC, IHC-P, IHC-F, ELISA
PAB839Mu02 Polyclonal Antibody to Vinculin (VCL) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB839Mu ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a