V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)
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C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS3; RASK2
 HGNC 6407
 MGI 96680
 PubMed 6308466
 RGD 2981
 UniProt P01116
 USCN H751
 Wiki KRAS
V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)
Like other members of the Ras family, the KRAS protein is a GTPase and is an early player in many signal transduction pathways. KRAS is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. When mutated, KRAS is a oncogene. The protein product of the normal KRAS gene performs an essential function in normal tissue signaling, and the mutation of a KRAS gene is an essential step in the development of many cancers.KRAS acts as a molecular on/off switch, once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. KRAS binds to GTP in the active state and possesses an intrinsic enzymatic activity which cleaves the terminal phosphate of the nucleotide converting it to GDP.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH751Hu01 Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) SDS-PAGE; WB; ELISA; IP.
Antibodies MAH751Hu21 Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) WB, ICC, IHC-P, IHC-F, ELISA
PAH751Hu01 Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEH751Hu ELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a