Uromodulin (UMOD)
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Uromucoid,Tamm-Horsfall Glycoprotein
 HGNC 12559
 MGI 102674
 PubMed 21071970
 RGD 3940
 UniProt P07911
 USCN G918
 Wiki Uromodulin
Uromodulin (UMOD)
Uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 and familial juvenile hyperuricemic nephropathy. These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG918Hu01 Recombinant Uromodulin (UMOD) SDS-PAGE; WB; ELISA; IP.
Antibodies PAG918Hu01 Polyclonal Antibody to Uromodulin (UMOD) WB, ICC, IHC-P, IHC-F, ELISA
PAG918Hu71 Biotin-Linked Antibody to Uromodulin (UMOD) IHC;WB;ELISA
Assay Kits SEG918Hu ELISA Kit for Uromodulin (UMOD) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG918Mu01 Recombinant Uromodulin (UMOD) SDS-PAGE; WB; ELISA; IP.
RPG918Mu02 Recombinant Uromodulin (UMOD) SDS-PAGE; WB; ELISA; IP.
Antibodies PAG918Mu01 Polyclonal Antibody to Uromodulin (UMOD) WB, ICC, IHC-P, IHC-F, ELISA
PAG918Mu02 Polyclonal Antibody to Uromodulin (UMOD) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEG918Mu ELISA Kit for Uromodulin (UMOD) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG918Ra01 Recombinant Uromodulin (UMOD) SDS-PAGE; WB; ELISA; IP.
Antibodies MAG918Ra21 Monoclonal Antibody to Uromodulin (UMOD) WB, ICC, IHC-P, IHC-F, ELISA
PAG918Ra01 Polyclonal Antibody to Uromodulin (UMOD) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEG918Ra ELISA Kit for Uromodulin (UMOD) Enzyme-linked immunosorbent assay