Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3)
Ubiquitin Thiolesterase; Ubiquitin thioesterase L3; Ubiquitin carboxyl-terminal hydrolase isozyme L3
Covalent attachment of the C terminus of ubiquitin to cellular proteins plays a role in a variety of cellular processes. Ubiquitin C-terminal hydrolysis is catalyzed by deubiquitinating (DUB) enzymes and is necessary for several functions, including liberation of monomeric ubiquitin from the precursors encoded by ubiquitin genes and recycling of ubiquitin monomers. There are 2 distinct families of DUBs, ubiquitin-specific proteases (UBPs) and ubiquitin C-terminal hydrolases (UCHs). By screening a human B-cell expression library with the antibodies, the authors isolated cDNAs encoding human UCHL3. The predicted 230-amino acid human UCHL3 protein is 54% identical to UCHL1.In adult tissues, Uchl3 was variably expressed in all tissues examined, with highest expression in testis.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPG944Hu01 | Recombinant Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAG944Hu01 | Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | WB; IHC; ICC; IP. |
LAG944Hu71 | Biotin-Linked Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | WB; IHC; ICC. | |
Assay Kits | n/a | CLIA Kit for Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPG944Ra01 | Recombinant Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAG944Ra01 | Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | WB; IHC; ICC; IP. |
LAG944Ra71 | Biotin-Linked Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | WB; IHC; ICC. | |
Assay Kits | n/a | CLIA Kit for Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) | ELISA Kit Customized Service Offer |