Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3)
Ubiquitin Thiolesterase
 HGNC 12515
 MGI 1355274
 RGD 621131
 UniProt P15374
 USCN G944
Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3)
Covalent attachment of the C terminus of ubiquitin to cellular proteins plays a role in a variety of cellular processes. Ubiquitin C-terminal hydrolysis is catalyzed by deubiquitinating (DUB) enzymes and is necessary for several functions, including liberation of monomeric ubiquitin from the precursors encoded by ubiquitin genes and recycling of ubiquitin monomers. There are 2 distinct families of DUBs, ubiquitin-specific proteases (UBPs) and ubiquitin C-terminal hydrolases (UCHs).
By screening a human B-cell expression library with the antibodies, the authors isolated cDNAs encoding human UCHL3. The predicted 230-amino acid human UCHL3 protein is 54% identical to UCHL1.In adult tissues, Uchl3 was variably expressed in all tissues examined, with highest expression in testis.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG944Hu01 Recombinant Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) SDS-PAGE; WB; ELISA; IP.
Antibodies PAG944Hu01 Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) WB, ICC, IHC-P, IHC-F, ELISA
PAG944Hu71 Biotin-Linked Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) IHC;WB;ELISA
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG944Ra01 Recombinant Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) SDS-PAGE; WB; ELISA; IP.
Antibodies PAG944Ra01 Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) WB, ICC, IHC-P, IHC-F, ELISA
PAG944Ra71 Biotin-Linked Antibody to Ubiquitin Carboxyl Terminal Hydrolase L3 (UCHL3) IHC;WB;ELISA
Assay Kits n/a n/a n/a