Twisted Gastrulation Protein Homolog 1 (TWSG1)

TSG

The cDNA encodes a protein sharing 41% amino acid identity with Drosophila Tsg, 89% identity with the partial human Tsg sequence, and 94% identity with a mouse EST. The Tsg sequence contains a signal peptide, as expected for a secreted protein, and 2 conserved domains containing multiple cysteines at its amino and carboxy termini. At the late gastrula stage, maternal transcripts decrease and zygotic transcripts appear, specifically in the ventral region of the embryo. Tsg has ventralizing activity and is a bone morphogenetic protein (BMP) binding protein. The N-terminal domain of Tsg is sufficient to interact with BMP4 but not with chordin. Tsg competes for binding of BMP4 with the first cysteine-rich domain of chordin (CR1) but not with full-length chordin. Endogenous Tsg antagonizes CR1 activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF862Hu01 Recombinant Twisted Gastrulation Protein Homolog 1 (TWSG1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF862Hu01 Polyclonal Antibody to Twisted Gastrulation Protein Homolog 1 (TWSG1) WB; IHC; ICC; IP.
MAF862Hu21 Monoclonal Antibody to Twisted Gastrulation Protein Homolog 1 (TWSG1) WB; IHC; ICC; IP.
Assay Kits SEF862Hu ELISA Kit for Twisted Gastrulation Protein Homolog 1 (TWSG1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Twisted Gastrulation Protein Homolog 1 (TWSG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Twisted Gastrulation Protein Homolog 1 (TWSG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Twisted Gastrulation Protein Homolog 1 (TWSG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Twisted Gastrulation Protein Homolog 1 (TWSG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Twisted Gastrulation Protein Homolog 1 (TWSG1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Twisted Gastrulation Protein Homolog 1 (TWSG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Twisted Gastrulation Protein Homolog 1 (TWSG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Twisted Gastrulation Protein Homolog 1 (TWSG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Twisted Gastrulation Protein Homolog 1 (TWSG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Twisted Gastrulation Protein Homolog 1 (TWSG1) ELISA Kit Customized Service Offer