Tumor Protein p53 (TP53)
p53; LFS1; TRP53; Li-Fraumeni Syndrome
 HGNC 11998
 MGI 98834
 RGD 3889
 UniProt P04637
 USCN A928
Tumor Protein p53 (TP53)
The p53 responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA928Hu01 Recombinant Tumor Protein p53 (TP53) SDS-PAGE; WB; ELISA; IP.
Antibodies MAA928Hu22 Monoclonal Antibody to Tumor Protein p53 (TP53) WB, ICC, IHC-P, IHC-F, ELISA
PAA928Hu01 Polyclonal Antibody to Tumor Protein p53 (TP53) WB, ICC, IHC-P, IHC-F, ELISA
PAA928Hu71 Biotin-Linked Antibody to Tumor Protein p53 (TP53) IHC;WB;ELISA
Assay Kits SEA928Hu ELISA Kit for Tumor Protein p53 (TP53) Enzyme-linked immunosorbent assay
SCA928Hu CLIA Kit for Tumor Protein p53 (TP53) Chemiluminescent immunoassay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA928Mu01 Recombinant Tumor Protein p53 (TP53) SDS-PAGE; WB; ELISA; IP.
RPA928Mu02 Recombinant Tumor Protein p53 (TP53) SDS-PAGE; WB; ELISA; IP.
Antibodies PAA928Mu01 Polyclonal Antibody to Tumor Protein p53 (TP53) WB, ICC, IHC-P, IHC-F, ELISA
PAA928Mu02 Polyclonal Antibody to Tumor Protein p53 (TP53) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEA928Mu ELISA Kit for Tumor Protein p53 (TP53) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA928Ra01 Recombinant Tumor Protein p53 (TP53) SDS-PAGE; WB; ELISA; IP.
Antibodies MAA928Ra21 Monoclonal Antibody to Tumor Protein p53 (TP53) WB, ICC, IHC-P, IHC-F, ELISA
PAA928Ra01 Polyclonal Antibody to Tumor Protein p53 (TP53) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEA928Ra ELISA Kit for Tumor Protein p53 (TP53) Enzyme-linked immunosorbent assay
Organism species: Oryctolagus cuniculus (Rabbit)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a