Tumor Protein p53 (P53)
TP53; LFS1; TRP53; Li-Fraumeni Syndrome; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
The p53 responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA928Hu01 | Recombinant Tumor Protein p53 (P53) | Positive Control; Immunogen; SDS-PAGE; WB. |
APA928Hu01 | Active Tumor Protein p53 (P53) | Cell culture; Activity Assays. | |
RPA928Hu02 | Recombinant Tumor Protein p53 (P53) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA928Hu03 | Recombinant Tumor Protein p53 (P53) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA928Hu01 | Polyclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. |
MAA928Hu22 | Monoclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
LAA928Hu71 | Biotin-Linked Polyclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC. | |
MAA928Hu21 | Monoclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
MAA928Hu23 | Monoclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
PAA928Hu02 | Polyclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
MAA928Hu24 | Monoclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
MAA928Hu25 | Monoclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
MAA928Hu27 | Monoclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
Assay Kits | SEA928Hu | ELISA Kit for Tumor Protein p53 (P53) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA928Hu | CLIA Kit for Tumor Protein p53 (P53) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA928Mu01 | Recombinant Tumor Protein p53 (P53) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA928Mu02 | Recombinant Tumor Protein p53 (P53) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA928Mu01 | Polyclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. |
PAA928Mu02 | Polyclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
Assay Kits | SEA928Mu | ELISA Kit for Tumor Protein p53 (P53) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA928Ra01 | Recombinant Tumor Protein p53 (P53) | Positive Control; Immunogen; SDS-PAGE; WB. |
APA928Ra01 | Active Tumor Protein p53 (P53) | Cell culture; Activity Assays. | |
Antibodies | PAA928Ra01 | Polyclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. |
MAA928Ra21 | Monoclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
MAA928Ra22 | Monoclonal Antibody to Tumor Protein p53 (P53) | WB; IHC; ICC; IP. | |
Assay Kits | SEA928Ra | ELISA Kit for Tumor Protein p53 (P53) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Tumor Protein p53 (P53) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Tumor Protein p53 (P53) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Tumor Protein p53 (P53) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Tumor Protein p53 (P53) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Tumor Protein p53 (P53) | ELISA Kit Customized Service Offer |