Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5)
Bp50; CD40; CDW40; P50
 HGNC 11919
 MGI 88336
 RGD 619830
 UniProt P25942
 USCN B249
Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5)
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB249Mu01 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) SDS-PAGE; WB; ELISA; IP.
RPB249Mu02 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB249Mu01 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) IWB, ICC, IHC-P, IHC-F, ELISA
PAB249Mu02 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB249Mu ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB249Ra01 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB249Ra21 Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) WB, ICC, IHC-P, IHC-F, ELISA
PAB249Ra01 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB249Ra ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5) Enzyme-linked immunosorbent assay