Tumor Necrosis Factor Receptor Superfamily, Member 10C (TNFRSF10C)
TNFRSF10-C; CD263; DCR1; LIT; TRAILR3; TRID
 HGNC 11906
 OMIM 603613
 UCSC uc003xcy.1
 UniProt O14798
 USCN 90137
 Wiki TNFRSF10C
Tumor Necrosis Factor Receptor Superfamily, Member 10C (TNFRSF10C)

Tumor necrosis factor receptor superfamily member 10C is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis.

TNFRSF10C was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Organism Manual
E90137HuELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 10C (TNFRSF10C)Homo sapiens (Human)  n/a
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Organism Manual
C90137HuCLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 10C (TNFRSF10C)Homo sapiens (Human)  n/a