Tumor Necrosis Factor Alpha (TNFa)
DIF; TNF-A; TNFSF2; TNF Superfamily,Member 2
DIF; TNF-A; TNFSF2; TNF Superfamily,Member 2
-90133.jpg "Tumor Necrosis Factor Alpha (TNFa)")
TNFa is synthesized as a 26 kDa, type II transmembrane protein that is 233 amino acids in length. It contains a 30 amino acid (aa) cytoplasmic domain, a 26 aa transmembrane segment, and a 177 aa extracellular region. TNFa is assembled intracellularly to form a transmembrane, non-covalently-linked homotrimeric protein. The 157 aa residue soluble form of TNFa (sTNF-αis released from the C-terminus of the transmembrane protein through the activity of TNFa-converting enzyme (TACE), a membrane -bound disintegrin metalloproteinase. Rat cells known to express TNF-αinclude B cells, colonic columnar epithelial cells, NK and CD3 CD56 hepatic natural T cells, macrophages, monocytes and monocyte-derived dendritic cells, CD4 and CD8 T cells, mast cells, neutrophils, keratinocytes, plasma cells, and adipocytes.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| E90133Hu | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Homo sapiens (Human) | |
| E90133Mu | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Mus musculus (Mouse) | |
| E90133Ra | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Rattus norvegicus (Rat) | |
| E90133Gu | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Cavia (Guinea pig ) | |
| E90133Rb | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Oryctolagus cuniculus (Rabbit) | |
| E90133Si | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Rhesus monkey (Simian) | |
| E90133Ca | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Canis familiaris; Canine (Dog) | |
| E90133Po | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Sus scrofa; Porcine (Pig) | |
| E90133Bo | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Bos taurus; Bovine (Cattle) | |
| E90133Cp | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Capra hircus; Caprine (Goat) | |
| E90133Eq | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Equus caballus; Equine (Horse) |
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| C90133Hu | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Homo sapiens (Human) | n/a |
| C90133Mu | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Mus musculus (Mouse) | n/a |
| C90133Ra | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Rattus norvegicus (Rat) | n/a |
| C90133Gu | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Cavia (Guinea pig ) | n/a |
| C90133Rb | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Oryctolagus cuniculus (Rabbit) | n/a |
| C90133Si | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Rhesus monkey (Simian) | n/a |
| C90133Ca | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Canis familiaris; Canine (Dog) | n/a |
| C90133Po | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Sus scrofa; Porcine (Pig) | n/a |
| C90133Bo | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Bos taurus; Bovine (Cattle) | n/a |
| C90133Cp | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Capra hircus; Caprine (Goat) | n/a |
| C90133Eq | CLIA Kit for Tumor Necrosis Factor Alpha (TNFa) | Equus caballus; Equine (Horse) | n/a |