Tripeptidyl Peptidase I (TPP1)
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CLN2; GIG1; LPIC; TPP I; Ceroid-Lipofuscinosis,Neuronal 2,Late Infantile(Jansky-Bielschowsky Disease)
 HGNC 2073
 MGI 1336194
 PubMed 24513288
 RGD 621296
 UniProt O14773
 USCN C828
 Wiki TPP1
Tripeptidyl Peptidase I (TPP1)
Tripeptidyl-peptidase 1 is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity.
It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.
 
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC828Hu01 Recombinant Tripeptidyl Peptidase I (TPP1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC828Hu22 Monoclonal Antibody to Tripeptidyl Peptidase I (TPP1) WB, ICC, IHC-P, IHC-F, ELISA
PAC828Hu01 Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC828Hu ELISA Kit for Tripeptidyl Peptidase I (TPP1) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC828Mu01 Recombinant Tripeptidyl Peptidase I (TPP1) SDS-PAGE; WB; ELISA; IP.
RPC828Mu02 Recombinant Tripeptidyl Peptidase I (TPP1) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC828Mu01 Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) IWB, ICC, IHC-P, IHC-F, ELISA
PAC828Mu02 Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC828Mu ELISA Kit for Tripeptidyl Peptidase I (TPP1) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a