Tripeptidyl Peptidase I (TPP1)
CLN2; GIG1; LPIC; Tripeptidyl aminopeptidase; Lysosomal pepstatin-insensitive protease; Ceroid-Lipofuscinosis,Neuronal 2,Late Infantile; Cell growth-inhibiting gene 1 protein
Tripeptidyl-peptidase 1 is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity.
It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC828Hu01 | Recombinant Tripeptidyl Peptidase I (TPP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC828Hu01 | Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) | WB; IHC; ICC; IP. |
MAC828Hu22 | Monoclonal Antibody to Tripeptidyl Peptidase I (TPP1) | WB; IHC; ICC; IP. | |
Assay Kits | SEC828Hu | ELISA Kit for Tripeptidyl Peptidase I (TPP1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC828Mu01 | Recombinant Tripeptidyl Peptidase I (TPP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC828Mu02 | Recombinant Tripeptidyl Peptidase I (TPP1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC828Mu01 | Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) | WB; IHC; ICC; IP. |
PAC828Mu02 | Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) | WB; IHC; ICC; IP. | |
Assay Kits | SEC828Mu | ELISA Kit for Tripeptidyl Peptidase I (TPP1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Tripeptidyl Peptidase I (TPP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Tripeptidyl Peptidase I (TPP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Tripeptidyl Peptidase I (TPP1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Tripeptidyl Peptidase I (TPP1) | ELISA Kit Customized Service Offer |