Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE)
PGPEP2; TRH-DE; PAP-II; Pyroglutamyl-Peptidase II; TRH-specific aminopeptidase; Thyroliberinase
Thyrotropin-releasing hormone (TRH) acts as a stimulator of hormone secretion from adenohypophyseal cells, and its signals are inactivated by TRH-degrading ectoenzyme.
The deduced 1,024-amino acid type II integral transmembrane protein is 96% identical to the rat protein. It has 12 putative C-terminal N-glycosylation sites, a potential tyrosine sulfation site (residue 380), a consensus sequence for zinc-dependent metallopeptidases, and a short N-terminal intracellular domain with a potential phosphorylation site. Northern blot analysis revealed expression of 7.5-, 7.0-, 6.0-, and 4.5-kb transcripts. Strongest expression was in brain, with weaker expression in heart, lung, liver, and skeletal muscle, and no expression in kidney and placenta.
The deduced 1,024-amino acid type II integral transmembrane protein is 96% identical to the rat protein. It has 12 putative C-terminal N-glycosylation sites, a potential tyrosine sulfation site (residue 380), a consensus sequence for zinc-dependent metallopeptidases, and a short N-terminal intracellular domain with a potential phosphorylation site. Northern blot analysis revealed expression of 7.5-, 7.0-, 6.0-, and 4.5-kb transcripts. Strongest expression was in brain, with weaker expression in heart, lung, liver, and skeletal muscle, and no expression in kidney and placenta.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thyrotropin Releasing Hormone Degrading Enzyme (TRHDE) | ELISA Kit Customized Service Offer |