Thyroid Peroxidase (TPO)
[ Edit ]
TPX; thyroperoxidase
 HGNC 12015
 MGI 98813
 PubMed 9360536
 RGD 3900
 UniProt P07202
 USCN A557
 Wiki TPO
Thyroid Peroxidase (TPO)
Thyroid peroxidase is an enzyme normally found in the thyroid gland, which plays an important role in the production of thyroid hormones. Fabrication of thyroid hormones is conducted by the enzyme thyroid peroxidase, an integral membrane protein present in the apical (colloid-facing) plasma membrane of thyroid epithelial cells.
Thyroid peroxidase catalyzes two sequential reactions: Iodination of tyrosines on thyroglobulin  Synthesis of thyroxine or triiodothyronine from two iodotyrosines. Through the action of thyroid peroxidase, thyroid hormones accumulate in colloid, on the surface of thyroid epithelial cells. Remember that hormone is still tied up in molecules of thyroglobulin - the task remaining is to liberate it from the scaffold and secrete free hormone into blood.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA557Hu01 Recombinant Thyroid Peroxidase (TPO) SDS-PAGE; WB; ELISA; IP.
Antibodies MAA557Hu22 Monoclonal Antibody to Thyroid Peroxidase (TPO) WB, ICC, IHC-P, IHC-F, ELISA
PAA557Hu01 Polyclonal Antibody to Thyroid Peroxidase (TPO) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEA557Hu ELISA Kit for Thyroid Peroxidase (TPO) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA557Mu01 Recombinant Thyroid Peroxidase (TPO) SDS-PAGE; WB; ELISA; IP.
RPA557Mu02 Recombinant Thyroid Peroxidase (TPO) SDS-PAGE; WB; ELISA; IP.
RPA557Mu03 Recombinant Thyroid Peroxidase (TPO) SDS-PAGE; WB; ELISA; IP.
Antibodies PAA557Mu01 Polyclonal Antibody to Thyroid Peroxidase (TPO) WB, ICC, IHC-P, IHC-F, ELISA
PAA557Mu02 Polyclonal Antibody to Thyroid Peroxidase (TPO) WB, ICC, IHC-P, IHC-F, ELISA
PAA557Mu71 Biotin-Linked Antibody to Thyroid Peroxidase (TPO) IHC;WB;ELISA
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA557Ra01 Recombinant Thyroid Peroxidase (TPO) SDS-PAGE; WB; ELISA; IP.
Antibodies MAA557Ra21 Monoclonal Antibody to Thyroid Peroxidase (TPO) WB, ICC, IHC-P, IHC-F, ELISA
PAA557Ra01 Polyclonal Antibody to Thyroid Peroxidase (TPO) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEA557Ra ELISA Kit for Thyroid Peroxidase (TPO) Enzyme-linked immunosorbent assay