Thyroid Peroxidase (TPO)
TPX; thyroperoxidase
Thyroid peroxidase is an enzyme normally found in the thyroid gland, which plays an important role in the production of thyroid hormones. Fabrication of thyroid hormones is conducted by the enzyme thyroid peroxidase, an integral membrane protein present in the apical (colloid-facing) plasma membrane of thyroid epithelial cells.
Thyroid peroxidase catalyzes two sequential reactions: Iodination of tyrosines on thyroglobulin Synthesis of thyroxine or triiodothyronine from two iodotyrosines. Through the action of thyroid peroxidase, thyroid hormones accumulate in colloid, on the surface of thyroid epithelial cells. Remember that hormone is still tied up in molecules of thyroglobulin - the task remaining is to liberate it from the scaffold and secrete free hormone into blood.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA557Hu01 | Recombinant Thyroid Peroxidase (TPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA557Hu01 | Polyclonal Antibody to Thyroid Peroxidase (TPO) | WB; IHC; ICC; IP. |
MAA557Hu22 | Monoclonal Antibody to Thyroid Peroxidase (TPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA557Hu | ELISA Kit for Thyroid Peroxidase (TPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA557Mu01 | Recombinant Thyroid Peroxidase (TPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA557Mu03 | Recombinant Thyroid Peroxidase (TPO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA557Mu02 | Recombinant Thyroid Peroxidase (TPO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA557Mu01 | Polyclonal Antibody to Thyroid Peroxidase (TPO) | WB; IHC; ICC; IP. |
PAA557Mu02 | Polyclonal Antibody to Thyroid Peroxidase (TPO) | WB; IHC; ICC; IP. | |
LAA557Mu71 | Biotin-Linked Polyclonal Antibody to Thyroid Peroxidase (TPO) | WB; IHC; ICC. | |
Assay Kits | n/a | CLIA Kit for Thyroid Peroxidase (TPO) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thyroid Peroxidase (TPO) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA557Ra01 | Recombinant Thyroid Peroxidase (TPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA557Ra01 | Polyclonal Antibody to Thyroid Peroxidase (TPO) | WB; IHC; ICC; IP. |
MAA557Ra21 | Monoclonal Antibody to Thyroid Peroxidase (TPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA557Ra | ELISA Kit for Thyroid Peroxidase (TPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
AEA557Ra | ELISA Kit for Anti-Thyroid Peroxidase Antibody (Anti-TPO) | Enzyme-linked immunosorbent assay for Antibody Detection. |