Telomerase Reverse Transcriptase (TERT)
[ Edit ]
EST2; TCS1; TP2; TRT; hEST2; Telomerase catalytic subunit; Telomerase-associated protein 2
 HGNC 11730
 MGI 1202709
 PubMed 16756500
 RGD 70494
 UniProt O14746
 USCN C241
 Wiki TERT
Telomerase Reverse Transcriptase (TERT)
Telomerase reverse transcriptase is a catalytic subunit of the enzyme telomerase. Its absence (usually as a result of a chromosomal mutation) is associated with the disorder Cri du chat.Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG.
The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC241Hu01 Recombinant Telomerase Reverse Transcriptase (TERT) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC241Hu22 Monoclonal Antibody to Telomerase Reverse Transcriptase (TERT) WB, ICC, IHC-P, IHC-F, ELISA
PAC241Hu01 Polyclonal Antibody to Telomerase Reverse Transcriptase (TERT) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC241Hu ELISA Kit for Telomerase Reverse Transcriptase (TERT) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC241Mu01 Recombinant Telomerase Reverse Transcriptase (TERT) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC241Mu01 Polyclonal Antibody to Telomerase Reverse Transcriptase (TERT) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC241Ra01 Recombinant Telomerase Reverse Transcriptase (TERT) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC241Ra21 Monoclonal Antibody to Telomerase Reverse Transcriptase (TERT) WB, ICC, IHC-P, IHC-F, ELISA
PAC241Ra01 Polyclonal Antibody to Telomerase Reverse Transcriptase (TERT) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC241Ra ELISA Kit for Telomerase Reverse Transcriptase (TERT) Enzyme-linked immunosorbent assay