T-Box Protein 5 (TBX5)
HOS; T-box transcription factor TBX5
TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.From the critical region they likewise isolated a gene with a high degree of homology to mouse Tbx5 and identified several mutations in TBX5 in affected members of HOS families.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant T-Box Protein 5 (TBX5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to T-Box Protein 5 (TBX5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to T-Box Protein 5 (TBX5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for T-Box Protein 5 (TBX5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for T-Box Protein 5 (TBX5) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH856Mu01 | Recombinant T-Box Protein 5 (TBX5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to T-Box Protein 5 (TBX5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to T-Box Protein 5 (TBX5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for T-Box Protein 5 (TBX5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for T-Box Protein 5 (TBX5) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant T-Box Protein 5 (TBX5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to T-Box Protein 5 (TBX5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to T-Box Protein 5 (TBX5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for T-Box Protein 5 (TBX5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for T-Box Protein 5 (TBX5) | ELISA Kit Customized Service Offer |