Suppressors Of Cytokine Signaling 1 (SOCS1)
CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP3; JAK-binding protein; STAT-induced STAT inhibitor 1; Tec-interacting protein 3
SOCS1 orthologs have been identified in several mammals for which complete genome data are available.This SOCS1 encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH158Hu01 | Recombinant Suppressors Of Cytokine Signaling 1 (SOCS1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAH158Hu01 | Polyclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1) | WB; IHC; ICC; IP. |
MAH158Hu21 | Monoclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1) | WB; IHC; ICC; IP. | |
Assay Kits | SEH158Hu | ELISA Kit for Suppressors Of Cytokine Signaling 1 (SOCS1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Suppressors Of Cytokine Signaling 1 (SOCS1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Suppressors Of Cytokine Signaling 1 (SOCS1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Suppressors Of Cytokine Signaling 1 (SOCS1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH158Ra01 | Recombinant Suppressors Of Cytokine Signaling 1 (SOCS1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAH158Ra21 | Monoclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1) | WB; IHC; ICC; IP. |
PAH158Ra01 | Polyclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1) | WB; IHC; ICC; IP. | |
Assay Kits | SEH158Ra | ELISA Kit for Suppressors Of Cytokine Signaling 1 (SOCS1) | Enzyme-linked immunosorbent assay for Antigen Detection. |