Succinate Dehydrogenase Complex Subunit D (SDHD)
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PGL; PGL1
 HGNC 10683
 MGI 1914175
 PubMed 1301144
 RGD 735231
 UniProt O14521
 USCN K214
 Wiki SDHD
Succinate Dehydrogenase Complex Subunit D (SDHD)
SDHD, which stands for succinate dehydrogenase complex subunit D, is one of the two transmembrane subunits of the four-subunit succinate dehydrogenase protein complex that resides in the inner mitochondrial membrane. It also refers to the gene that codes for this protein.
Germline mutations in SDHD were first linked to hereditary paraganglioma in 2000. Since then, it has been shown that mutations in SDHB and to a lesser degree SDHC can cause paranglioma as well familial pheochromocytoma. Notably, the tumor spectrum is different for the different mutations. SDHB mutations often lead to metastatic disease that is extra-adrenal, while SDHD mutation related tumors are more typically benign, originating in the head and neck.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPK214Mu01 Recombinant Succinate Dehydrogenase Complex Subunit D (SDHD) SDS-PAGE; WB; ELISA; IP.
RPK214Mu02 Recombinant Succinate Dehydrogenase Complex Subunit D (SDHD) SDS-PAGE; WB; ELISA; IP.
Antibodies PAK214Mu01 Polyclonal Antibody to Succinate Dehydrogenase Complex Subunit D (SDHD) IWB, ICC, IHC-P, IHC-F, ELISA
PAK214Mu02 Polyclonal Antibody to Succinate Dehydrogenase Complex Subunit D (SDHD) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEK214Mu ELISA Kit for Succinate Dehydrogenase Complex Subunit D (SDHD) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a