Sphingomyelin(SPH)
SM
USCNK 90805
W i  k  i SPH
Sphingomyelin(SPH)
Sphingomyelin (SPH), is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath which surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide. In humans SPH represents ~85% of all sphingolipids. In humans, sphingomyelin is believed to be the only cell membrane phospholipid not derived from glycerol.
Like all sphingolipids, SPH has a ceramide core (sphingosine bonded to a fatty acid via an amide linkage). In addition it contains one polar head group, which is either phosphocholine or phosphoethanolamine.The plasma membrane of cells is highly enriched in sphingomyelin and is considered largely to be found in the exoplasmic leaflet of the cell membrane.
However, there is some evidence that there may also be a sphingomyelin pool in the inner leaflet of the membrane. Moreover, neutral sphingomyelinase-2 an enzyme that breaks down sphingomyelin into ceramide has been found to localise exclusively to the inner leaflet further suggesting that there may be sphingomyelin present there.
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Species Packing Price Manual
E90805HuELISA Kit for Human Sphingomyelin(SPH)Human96T$700   PDF
E90805MuELISA Kit for Mouse Sphingomyelin(SPH)Mouse96T$720   PDF
 Antibodies
Catalog Product Name Species Packing Price Manual
A90805HuAntibody to Human Sphingomyelin(SPH)Humann/an/a   n/a
A90805MuAntibody to Mouse Sphingomyelin(SPH)Mousen/an/a   n/a
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Species Packing Price Manual
C90805HuCLIA Kit for Human Sphingomyelin(SPH)Humann/an/a   n/a
C90805MuCLIA Kit for Mouse Sphingomyelin(SPH)Mousen/an/a   n/a