Membrane Associated Transporter (MATP)
SLC45A2; AIM1; 1A1; Solute Carrier Family 45 Member 2; Melanoma Antigen
 HGNC 16472
 MGI 2153040
 PubMed 23190901
 RGD 1306690
 UniProt Q9UMX9
 USCN E513
 Wiki SLC45A2
Membrane Associated Transporter (MATP)
SLC45A2 is a transporter protein that mediates melanin synthesis. SLC45A2 is also a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. A similar sequence gene in medaka, 'B,' encodes a transporter that mediates melanin synthesis. Mutations in this gene are a cause of oculocutaneous albinism type 4. Alternative splicing results in multiple transcript variants encoding different isoforms.In melanocytic cell types, the SLC45A2 gene is regulated by microphthalmia-associated transcription factor.AIM1 gene was expressed in 3 melanoma cell lines, but not in a fibroblast cell line, and not at significant levels in any of 15 normal tissues. The human AIM1 gene encodes a protein of 530 amino acids. Northern blot analysis detected 2 transcripts, one of 1.7 kb and the other of 2.8 kb.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a