Thiamine Transporter Protein 1 (THTR1)

SLC19A2; TRMA; TC1; THT1; Solute Carrier Family 19 Member 2; Thiamine carrier 1

Thiamine-responsive megaloblastic anemia syndrome (TRMA), is an early-onset, autosomal recessive disorder defined by the occurrence of megaloblastic anemia, diabetes mellitus, and sensorineural deafness, responding in varying degrees to thiamine treatment.The SLC19A2 gene encodes a protein of 497 amino acids predicted to have 12 transmembrane domains. Northern blot analysis detected a 4-kb transcript in all tissues tested, most abundantly in skeletal and cardiac muscle. Labay et al. (1999) identified the SLC19A2 gene by positional cloning. They assembled a P1-derived artificial chromosome (PAC) contig spanning the TRMA candidate region. This clarified the order of genetic markers across the TRMA locus, provided 9 new polymorphic markers, and narrowed the locus to an approximately 400-kb region.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thiamine Transporter Protein 1 (THTR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thiamine Transporter Protein 1 (THTR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thiamine Transporter Protein 1 (THTR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thiamine Transporter Protein 1 (THTR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thiamine Transporter Protein 1 (THTR1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thiamine Transporter Protein 1 (THTR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thiamine Transporter Protein 1 (THTR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thiamine Transporter Protein 1 (THTR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thiamine Transporter Protein 1 (THTR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thiamine Transporter Protein 1 (THTR1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thiamine Transporter Protein 1 (THTR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thiamine Transporter Protein 1 (THTR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thiamine Transporter Protein 1 (THTR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thiamine Transporter Protein 1 (THTR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thiamine Transporter Protein 1 (THTR1) ELISA Kit Customized Service Offer