Snurportin 1 (SNUPN1)
KPNBL; RNUT1; RNA, U Transporter 1
 HGNC 14245
 MGI 1913319
 OMIM 607902
 RGD 1303191
 UCSC uc002bas.2
 UniProt O95149
 USCN 92863
Snurportin 1 (SNUPN1)
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain.
Snurportin-1 is a protein  interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
Research reagent products of Snurportin 1 (SNUPN1)
Organism
Protein
Antibody
ELISA Kit
CLIA Kit
Catalog Manual McAb PcAb Catalog Manual Catalog Manual
Homo sapiens (Human)n/an/an/an/a n/an/an/an/a
Mus musculus (Mouse)n/an/an/an/a n/an/an/an/a
Rattus norvegicus (Rat)n/an/an/an/a n/an/an/an/a