Snail Homolog 2 (SNAI2)
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SLUG; SLUGH1; WS2D; Slug Homolog,Zinc Finger Protein
 HGNC 11094
 MGI 1096393
 PubMed 21647877
 RGD 3722
 UniProt O43623
 USCN L134
 Wiki SNAI2
Snail Homolog 2 (SNAI2)
SNAI2 encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects.
The deduced 268-amino acid protein has a calculated molecular mass of approximately 30 kD. It contains 5 zinc finger regions and shares 95% amino acid identity with mouse Slug. Northern blot analysis revealed a 2.2-kb SLUG transcript in placenta and adult heart, pancreas, liver, kidney, and skeletal muscle.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a