Signal Transducer And Activator Of Transcription 3 (STAT3)

APRF; Acute-Phase Response Factor

    STAT3, a transcription factor for acute phase response genes, acts as an adaptor molecule in signal transduction from the type I interferon receptor. They found that it binds to a conserved sequence in the cytoplasmic tail of the IFNAR1 chain of the receptor and undergoes interferon-dependent tyrosine phosphorylation. The p85 regulatory subunit of phosphatidylinositol 3-kinase, which activates a series of serine kinases, was found to bind to phosphorylated STAT3 and subsequently to undergo tyrosine phosphorylation. The authors concluded that STAT3 acts as an adaptor to couple another signaling pathway to the interferon receptor.In many human cancers and transformed cell lines, STAT3 is persistently activated, and in cell culture, active STAT3 is either required for transformation, enhances transformation, or blocks apoptosis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB743Mi01 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi02 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi03 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi04 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi05 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
APB743Hu01 Active Signal Transducer And Activator Of Transcription 3 (STAT3) Cell culture; Activity Assays.
RPB743Hu02 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Hu01 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB743Mi03 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi01 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi02 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi04 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi05 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Hu01 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi22 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi23 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi24 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi21 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi25 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi27 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
Assay Kits SEB743Mi ELISA Kit for Signal Transducer And Activator Of Transcription 3 (STAT3) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB743Hu ELISA Kit for Signal Transducer And Activator Of Transcription 3 (STAT3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB743Mi01 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi02 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi03 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi04 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi05 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mu02 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mu04 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB743Mi03 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi01 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi02 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi04 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi05 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi22 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi23 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi24 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi21 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi25 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
Assay Kits SEB743Mi ELISA Kit for Signal Transducer And Activator Of Transcription 3 (STAT3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB743Ra02 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi01 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi02 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi03 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi04 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi05 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Ra03 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Ra01 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB743Ra02 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi03 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi01 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi04 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi05 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Ra01 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi22 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi23 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi24 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi21 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
MAB743Mi25 Monoclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
Assay Kits SEB743Mi ELISA Kit for Signal Transducer And Activator Of Transcription 3 (STAT3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB743Bo01 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi01 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi02 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi03 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi04 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB743Mi05 Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3) Positive Control; Immunogen; SDS-PAGE; WB.
APB743Bo01 Active Signal Transducer And Activator Of Transcription 3 (STAT3) Cell culture; Activity Assays.
Antibodies PAB743Bo01 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
LAB743Bo71 Biotin-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC.
PAB743Mi03 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi01 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi04 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
PAB743Mi05 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Signal Transducer And Activator Of Transcription 3 (STAT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Signal Transducer And Activator Of Transcription 3 (STAT3) ELISA Kit Customized Service Offer