Serine Peptidase Inhibitor Kazal Type 5 (SPINK5)
LEKTI; LETKI; NETS; NS; VAKTI; Lymphoepithelial Kazal-Type-Related Inhibitor; Lympho-epithelial Kazal-type-related inhibitor
SPINK5 encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy.The entire precursor protein, as deduced from the nucleotide sequence of the cloned cDNA, includes 15 potential inhibitory domains, 13 of which exhibit a Kazal-type-derived 4-cysteine-residue pattern that represents a novel protein module of serine protease inhibitor. Northern blot analysis and RT-PCR detected expression of LEKTI in thymus, vaginal epithelium, Bartholin gland, oral mucosa, tonsil, and parathyroid gland.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH145Hu01 | Recombinant Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAH145Hu01 | Polyclonal Antibody to Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | WB; IHC; ICC; IP. |
MAH145Hu21 | Monoclonal Antibody to Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | WB; IHC; ICC; IP. | |
LAH145Hu71 | Biotin-Linked Polyclonal Antibody to Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | WB; IHC; ICC. | |
Assay Kits | SEH145Hu | ELISA Kit for Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH145Mu01 | Recombinant Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPH145Mu02 | Recombinant Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAH145Mu01 | Polyclonal Antibody to Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | WB; IHC; ICC; IP. |
PAH145Mu02 | Polyclonal Antibody to Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | WB; IHC; ICC; IP. | |
Assay Kits | SEH145Mu | ELISA Kit for Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) | ELISA Kit Customized Service Offer |