Serine Peptidase Inhibitor Kazal Type 1 (SPINK1)
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PCTT; PSTI; TATI; Tumor-Associated Trypsin Inhibitor
 HGNC 11244
 MGI 106202
 PubMed 21610753
 RGD 3749
 UniProt P00995
 USCN H143
 Wiki SPINK1
Serine Peptidase Inhibitor Kazal Type 1 (SPINK1)
SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.The 79-amino acid sequence contains a 23-amino acid signal peptide followed directly by the 56-amino acid mature secreted form.
Tumor-associated trypsin inhibitor (TATI) is identical to PSTI. TATI is a 6-kD peptide that is synthesized by several tumors and cell lines. It was initially detected in urine of patients with ovarian cancer .This peptide is also produced by the mucosa of the gastrointestinal tract where it may protect the mucosal cells from proteolytic breakdown.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH143Hu01 Recombinant Serine Peptidase Inhibitor Kazal Type 1 (SPINK1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAH143Hu21 Monoclonal Antibody to Serine Peptidase Inhibitor Kazal Type 1 (SPINK1) WB, ICC, IHC-P, IHC-F, ELISA
PAH143Hu01 Polyclonal Antibody to Serine Peptidase Inhibitor Kazal Type 1 (SPINK1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEH143Hu ELISA Kit for Serine Peptidase Inhibitor Kazal Type 1 (SPINK1) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a