SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1)
HARP; HHARP; HepA-Related Protein; ATP-Driven Annealing Helicase; Sucrose nonfermenting protein 2-like 1
SMARCAL1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. HARP bound with higher affinity to forked DNA than to single-stranded DNA (sDNA) or double-stranded DNA (dsDNA). HARP had ATPase activity that was stimulated by forked DNA, and to a lesser extent by ssDNA and dsDNA.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) | ELISA Kit Customized Service Offer |