Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
SCYA5; CCL5; SISd; TCP228; Chemokine C-C-Motif Ligand 5; T-cell Specific Protein p288; Small Inducible Cytokine Subfamily A(Cys-Cys)Member 5
SCYA5; CCL5; SISd; TCP228; Chemokine C-C-Motif Ligand 5; T-cell Specific Protein p288; Small Inducible Cytokine Subfamily A(Cys-Cys)Member 5
-90116.jpg "Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)")
Regulated on activation in normal T cell expressed and secreted(RANTES) was identified in 1988, as a result of a subtractive hybridization screen for mRNA expressed by T cells, but not by B cells. In addition to T cells, RANTES is also produced by epithelial cells, monocytes, fibroblasts, and mesanglial cells. Platelets and eosinophils release RANTES from intracellular storage granules upon activation. Several high affinity receptors for RANTES have been described, including CCR1, CCR3, CCR5, and cytomegalovirus receptor US28. RANTES also binds to the erythrocyte Duffy antigen receptor (DARC) with low affinity. RANTES regulates the trafficking of cells expressing these receptors, including T cells, eosinophils, basophils, monocytes, macrophages, microglia, NK cells, dendritic cells, mast cells, and neurons.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| C90116Hu | CLIA Kit for Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) | Homo sapiens (Human) | n/a |
| C90116Mu | CLIA Kit for Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) | Mus musculus (Mouse) | n/a |
| C90116Ra | CLIA Kit for Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) | Rattus norvegicus (Rat) | n/a |
| C90116Gu | CLIA Kit for Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) | Cavia (Guinea pig ) | n/a |
| C90116Si | CLIA Kit for Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) | Rhesus monkey (Simian) | n/a |
| C90116Ca | CLIA Kit for Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) | Canis familiaris; Canine (Dog) | n/a |
| C90116Po | CLIA Kit for Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) | Sus scrofa; Porcine (Pig) | n/a |
| C90116Bo | CLIA Kit for Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) | Bos taurus; Bovine (Cattle) | n/a |