Recombination Activating Gene 2 (RAG2)
RAG2 encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Recombination Activating Gene 2 (RAG2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Recombination Activating Gene 2 (RAG2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Recombination Activating Gene 2 (RAG2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Recombination Activating Gene 2 (RAG2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Recombination Activating Gene 2 (RAG2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Recombination Activating Gene 2 (RAG2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Recombination Activating Gene 2 (RAG2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Recombination Activating Gene 2 (RAG2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Recombination Activating Gene 2 (RAG2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Recombination Activating Gene 2 (RAG2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Recombination Activating Gene 2 (RAG2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Recombination Activating Gene 2 (RAG2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Recombination Activating Gene 2 (RAG2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Recombination Activating Gene 2 (RAG2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Recombination Activating Gene 2 (RAG2) | ELISA Kit Customized Service Offer |