R-Spondin 4 (RSPO4)
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C20orf182
 HGNC 16175
 MGI 1924467
 RGD 1563415
 UniProt Q2I0M5
 USCN P129
R-Spondin 4 (RSPO4)
RSPO4 encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.
The 224-amino acid human RSPO4 protein, like other members of the RSPO family, contains an N-terminal signal peptide, 2 furin-like domains, a thrombospondin type-1 (THBS1) domain, and a C-terminal low-complexity region enriched with positively charged amino acids. Dot blot analysis revealed very weak expression of RSPO4 in adult organs and tumors.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
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Antibodies n/a n/a n/a
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Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
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Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
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Assay Kits n/a n/a n/a