Proteinase 3 (PR3)
MBN; PRTN3; ACPA; AGP7; C-ANCA; MBT; P29; PRK; Myeloblastin; Serine Proteinase,Neutrophil,Wegener Granulomatosis Autoantigen
PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Proteinase K is commonly used in molecular biology to digest protein and remove contamination from preparations of nucleic acid. Addition of proteinase K to nucleic acid preparations rapidly inactivates nucleases that might otherwise degrade the DNA or RNA during purification.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB434Hu01 | Recombinant Proteinase 3 (PR3) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB434Hu02 | Recombinant Proteinase 3 (PR3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB434Hu01 | Polyclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC; IP. |
MAB434Hu22 | Monoclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC; IP. | |
PAB434Hu02 | Polyclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC; IP. | |
Assay Kits | SEB434Hu | ELISA Kit for Proteinase 3 (PR3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
AEB434Hu | ELISA Kit for Anti-Proteinase 3 Antibody (Anti-PR3) | Enzyme-linked immunosorbent assay for Antibody Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB434Mu01 | Recombinant Proteinase 3 (PR3) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB434Mu02 | Recombinant Proteinase 3 (PR3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB434Mu01 | Polyclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC; IP. |
LAB434Mu71 | Biotin-Linked Polyclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC. | |
PAB434Mu02 | Polyclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC; IP. | |
Assay Kits | SEB434Mu | ELISA Kit for Proteinase 3 (PR3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB434Ra01 | Recombinant Proteinase 3 (PR3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB434Ra01 | Polyclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC; IP. |
LAB434Ra71 | Biotin-Linked Polyclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC. | |
MAB434Ra21 | Monoclonal Antibody to Proteinase 3 (PR3) | WB; IHC; ICC; IP. | |
Assay Kits | SEB434Ra | ELISA Kit for Proteinase 3 (PR3) | Enzyme-linked immunosorbent assay for Antigen Detection. |