Proteinase 3 (PR3)
PRTN3; ACPA; AGP7; C-ANCA; MBT; P29; PRK; Serine Proteinase,Neutrophil,Wegener Granulomatosis Autoantigen; Protease K; Proteinase K; Endopeptidase K
 HGNC 9495
 MGI 893580
 RGD 1304898
 UniProt P24158
 USCN B434
Proteinase 3 (PR3)
PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Proteinase K is commonly used in molecular biology to digest protein and remove contamination from preparations of nucleic acid. Addition of proteinase K to nucleic acid preparations rapidly inactivates nucleases that might otherwise degrade the DNA or RNA during purification.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB434Hu01 Recombinant Proteinase 3 (PR3) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB434Hu22 Monoclonal Antibody to Proteinase 3 (PR3) WB, ICC, IHC-P, IHC-F, ELISA
PAB434Hu01 Polyclonal Antibody to Proteinase 3 (PR3) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB434Hu ELISA Kit for Proteinase 3 (PR3) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB434Mu01 Recombinant Proteinase 3 (PR3) SDS-PAGE; WB; ELISA; IP.
RPB434Mu02 Recombinant Proteinase 3 (PR3) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB434Mu01 Polyclonal Antibody to Proteinase 3 (PR3) WB, ICC, IHC-P, IHC-F, ELISA
PAB434Mu02 Polyclonal Antibody to Proteinase 3 (PR3) IWB, ICC, IHC-P, IHC-F, ELISA
PAB434Mu71 Biotin-Linked Antibody to Proteinase 3 (PR3) IHC;WB;ELISA
Assay Kits SEB434Mu ELISA Kit for Proteinase 3 (PR3) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB434Ra01 Recombinant Proteinase 3 (PR3) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB434Ra21 Monoclonal Antibody to Proteinase 3 (PR3) WB, ICC, IHC-P, IHC-F, ELISA
PAB434Ra01 Polyclonal Antibody to Proteinase 3 (PR3) WB, ICC, IHC-P, IHC-F, ELISA
PAB434Ra71 Biotin-Linked Antibody to Proteinase 3 (PR3) IHC;WB;ELISA
Assay Kits SEB434Ra ELISA Kit for Proteinase 3 (PR3) Enzyme-linked immunosorbent assay