Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)
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BPTP3; CFC; MGC14433; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2; Noonan Syndrome 1
 HGNC 9644
 MGI 99511
 PubMed 11704759
 RGD 3447
 UniProt Q06124
 USCN D584
 Wiki PTPN11
Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)
PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates.
This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD584Ra01 Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) SDS-PAGE; WB; ELISA; IP.
Antibodies MAD584Ra21 Monoclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) WB, ICC, IHC-P, IHC-F, ELISA
PAD584Ra01 Polyclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SED584Ra ELISA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) Enzyme-linked immunosorbent assay