Cyclooxygenase-2 (COX 2)
PGG/HS; PGHS2; PHS2; HCox2; PTGS2; Prostaglandin Endoperoxide Synthase 2; Prostaglandin G/H Synthase And Cyclooxygenase; Prostaglandin H2 synthase 2
Cyclooxygenase (COX) enzymes catalyze the synthesis of prostaglandins (PGs) from arachidonic acid. There are two isoforms of COX, COX-1 and COX-2. While COX-1 is expressed constitutively and appears to be responsible for the production of prostaglandins (PGs) that control normal physiologic functions, expression of COX-2 is induced by various inflammatory and mitogenic stimuli such as cytokines, growth factors or tumor promoters. Numerous experimental studies suggest a relationship between COX-2 expression and carcinogenesis. For example, increased amounts of COX-2 have been observed in breast cancers that overexpress HER-2/neu. Furthermore, treatment with selective inhibitors of COX-2 reduced the formation of tongue, esophagal, intestinal, breast, skin, lung, and bladder tumors in experimental animals.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA699Hu01 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA699Hu02 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA699Hu03 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA699Hu01 | Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. |
MAA699Hu22 | Monoclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. | |
PAA699Hu02 | Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. | |
Assay Kits | SEA699Hu | ELISA Kit for Cyclooxygenase-2 (COX 2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA699Mu01 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA699Mu02 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA699Mu01 | Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. |
LAA699Mu71 | Biotin-Linked Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC. | |
LAA699Mu81 | FITC-Linked Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IF. | |
PAA699Mu02 | Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. | |
Assay Kits | SEA699Mu | ELISA Kit for Cyclooxygenase-2 (COX 2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA699Ra01 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA699Ra01 | Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. |
MAA699Ra21 | Monoclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. | |
Assay Kits | SEA699Ra | ELISA Kit for Cyclooxygenase-2 (COX 2) | Enzyme-linked immunosorbent assay for Antigen Detection. |