Postmeiotic Segregation Increased Protein 1 (PMS1)
HNPCC3; PMSL1; hPMS1
 HGNC 9121
 MGI 1202302
 PubMed 15638857
 RGD 1359511
 UniProt P54277
 USCN M037
 Wiki PMS1
Postmeiotic Segregation Increased Protein 1 (PMS1)
PMS1 was identified by its homology to a yeast protein involved in DNA mismatch repair. A role for this protein in mismatch repair has not been proven. However, the protein forms heterodimers with MLH1, a DNA mismatch repair protein, and some cases of hereditary nonpolyposis colorectal cancer have been found to have mutations in this gene.
Sequence analysis of human PMS1 cDNA identified an open reading frame (ORF) of 2,795 bp thought to encode a 932-residue protein with 27% identity to yeast PMS1. Sequence analysis of the human PMS2 clone identified a 2,586-bp ORF thought to encode an 862-residue protein with 32% identity to yeast PMS1.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a