Polyglutamine Binding Protein 1 (PQBP1)
RENS1; MRXS8; SHS; MRX55; Sutherland-Haan X-Linked Mental Retardation Syndrome; Mental Retardation,X-Linked 55
 HGNC 9330
 MGI 1859638
 RGD 1549750
 UniProt O60828
 USCN H324
Polyglutamine Binding Protein 1 (PQBP1)
PQBP1 encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked mental retardation. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
The deduced 265-amino acid PQBP1 protein contains an N-terminal WW domain, a protein-protein interaction motif that has 2 conserved trp (W) residues, which lies between an acidic region and an acidic-basic amino acid repetitive region. PQBP1 also has a putative nuclear localization signal.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a