Pleckstrin Homology Like Domain Family A Member 2(PHLDA2)
PHLD-A2; BRW1C; BWR1C; HLDA2; IPL; TSSC3; Tumor Suppressing Subtransferable Candidate 3
Pleckstrin homology-like domain, family A, member 2, also known as PHLDA2, is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth.The IPL gene lies in an extended imprinted region of distal mouse chromosome 7, which also contains the IGF2 gene. Expression of Ipl is highest in placenta and yolk sac, where its mRNA is derived almost entirely from the maternal allele.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Antibodies
| Catalog |
Product Name |
Species |
Packing |
Price |
Manual |
| A90401Hu | Antibody to Human Pleckstrin Homology Like Domain Family A Member 2(PHLDA2) | Human | n/a | n/a | n/a |
| A90401Mu | Antibody to Mouse Pleckstrin Homology Like Domain Family A Member 2(PHLDA2) | Mouse | n/a | n/a | n/a |
| A90401Ra | Antibody to Rat Pleckstrin Homology Like Domain Family A Member 2(PHLDA2) | Rat | n/a | n/a | n/a |
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog |
Product Name |
Species |
Packing |
Price |
Manual |
| C90401Hu | CLIA Kit for Human Pleckstrin Homology Like Domain Family A Member 2(PHLDA2) | Human | n/a | n/a | n/a |
| C90401Mu | CLIA Kit for Mouse Pleckstrin Homology Like Domain Family A Member 2(PHLDA2) | Mouse | n/a | n/a | n/a |
| C90401Ra | CLIA Kit for Rat Pleckstrin Homology Like Domain Family A Member 2(PHLDA2) | Rat | n/a | n/a | n/a |