Glycoprotein VI, Platelet (GP6)
GPIV; GP-VI
 HGNC 14388
 MGI 1889810
 PubMed 19065783
 UniProt Q9HCN6
 USCN B904
 Wiki GPVI
Glycoprotein VI, Platelet (GP6)
Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets. Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels. Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB904Hu01 Recombinant Glycoprotein VI, Platelet (GP6) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB904Hu22 Monoclonal Antibody to Glycoprotein VI, Platelet (GP6) WB, ICC, IHC-P, IHC-F, ELISA
PAB904Hu01 Polyclonal Antibody to Glycoprotein VI, Platelet (GP6) WB, ICC, IHC-P, IHC-F, ELISA
PAB904Hu71 Biotin-Linked Antibody to Glycoprotein VI, Platelet (GP6) IHC;WB;ELISA
Assay Kits SEB904Hu ELISA Kit for Glycoprotein VI, Platelet (GP6) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a