Glycoprotein VI (GP6)
GPIV; GP-VI; Glycoprotein VI, Platelet
Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets. Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels. Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB904Hu01 | Recombinant Glycoprotein VI (GP6) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB904Hu01 | Polyclonal Antibody to Glycoprotein VI (GP6) | WB; IHC; ICC; IP. |
MAB904Hu22 | Monoclonal Antibody to Glycoprotein VI (GP6) | WB; IHC; ICC; IP. | |
LAB904Hu71 | Biotin-Linked Polyclonal Antibody to Glycoprotein VI (GP6) | WB; IHC; ICC. | |
Assay Kits | SEB904Hu | ELISA Kit for Glycoprotein VI (GP6) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Glycoprotein VI (GP6) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Glycoprotein VI (GP6) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Glycoprotein VI (GP6) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Glycoprotein VI (GP6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Glycoprotein VI (GP6) | ELISA Kit Customized Service Offer |