Plasminogen Activator Inhibitor 1 (PAI1)
SERPINE1; PLANH1; Serpin Peptidase Inhibitor Clade E Member 1; Nexin,Plasminogen Activator Inhibitor Type 1 Serpin E1; Endothelial plasminogen activator inhibitor
Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). It is a serine protease inhibitor (serpin) protein (SERPINE1).
The other PAI, plasminogen activator inhibitor-2 (PAI-2) is secreted by the placenta and only present in significant amounts during pregnancy. In addition, protease nexin acts as an inhibitor of tPA and urokinase. PAI-1, however, is the main inhibitor of the plasminogen activators. PAI-1 is mainly produced by the endothelium (cells lining blood vessels), but is also secreted by other tissue types, such as adipose tissue.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA532Mu01 | Recombinant Plasminogen Activator Inhibitor 1 (PAI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA532Mu02 | Recombinant Plasminogen Activator Inhibitor 1 (PAI1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| RPA532Mu03 | Recombinant Plasminogen Activator Inhibitor 1 (PAI1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| EPA532Mu61 | Eukaryotic Plasminogen Activator Inhibitor 1 (PAI1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA532Mu01 | Polyclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | WB; IHC; ICC; IP. |
| PAA532Mu02 | Polyclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA532Mu | ELISA Kit for Plasminogen Activator Inhibitor 1 (PAI1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA532Ra01 | Recombinant Plasminogen Activator Inhibitor 1 (PAI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA532Ra01 | Polyclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | WB; IHC; ICC; IP. |
| MAA532Ra21 | Monoclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA532Ra | ELISA Kit for Plasminogen Activator Inhibitor 1 (PAI1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA532Ra | CLIA Kit for Plasminogen Activator Inhibitor 1 (PAI1) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA532Rb01 | Recombinant Plasminogen Activator Inhibitor 1 (PAI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA532Rb51 | Polyclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | WB; IHC; ICC; IP. |
| MAA532Rb21 | Monoclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA532Rb | ELISA Kit for Plasminogen Activator Inhibitor 1 (PAI1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rhesus monkey (Simian)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA532Si01 | Recombinant Plasminogen Activator Inhibitor 1 (PAI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA532Si01 | Polyclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | WB; IHC; ICC; IP. |
| MAA532Si21 | Monoclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA532Si | ELISA Kit for Plasminogen Activator Inhibitor 1 (PAI1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Plasminogen Activator Inhibitor 1 (PAI1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Plasminogen Activator Inhibitor 1 (PAI1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Plasminogen Activator Inhibitor 1 (PAI1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Plasminogen Activator Inhibitor 1 (PAI1) | ELISA Kit Customized Service Offer |