Protein Interacting With Protein Kinase C Alpha 1 (PICK1)
PRKCABP; Protein kinase C,Alpha Binding Protein
 HGNC 9394
 MGI 894645
 OMIM 605926
 RGD 69437
 UCSC uc003aus.2
 UniProt Q9NRD5
 USCN 90931
Protein Interacting With Protein Kinase C Alpha 1 (PICK1)
PRKCA-binding protein is a protein contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function.
This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
Research reagent products of Protein Interacting With Protein Kinase C Alpha 1 (PICK1)
Organism
ELISA Kit
CLIA Kit
Protein
Antibody
Catalog Manual Catalog Manual Catalog Manual McAb PcAb
Homo sapiens (Human)E90931Hun/an/an/aP90931Hu01n/aA90931Hu22A90931Hu01
Mus musculus (Mouse)E90931Mun/an/an/aP90931Mu01n/an/aA90931Mu01
Rattus norvegicus (Rat)E90931Ran/an/an/aP90931Ra01n/an/aA90931Ra01